"Bivalent chromatin"

Stable DNMT3L overexpression in SH-SY5Y neurons recreates a facet of the genome-wide Down syndrome DNA methylation signature

Background: Down syndrome (DS) is characterized by a genome-wide profile of differential DNA methylation that is skewed towards …

Benjamin I. Laufer, J. Antonio Gomez, Julia M. Jianu, Janine M. LaSalle