Ben Laufer
Ben Laufer
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Automatic
Research
Placental Footprints of Neurodevelopment
Cell-free fetal DNA and placenta contain a subset of differentially methylated regions that reflect brain DNA methylation profiles.
Genetic Impacts on the Epigenome
Over-expression of
DNMT3L
and
RUNX1
contributes to regional DNA hypermethylation and DNA hypomethylation in Down syndrome brain and blood, respectively.
Environmental Impacts on the Epigenome
DNA hypermethylation of the clustered protocadherins is a conserved signature in adult brains from a mouse model of prenatal alcohol exposure and in buccal swabs from human children with fetal alcohol spectrum disorders (FASD).
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